The NYT has an article suggesting President Obama’s choice for “drug czar” (the head of the Office of National Drug Control Policy) could substantially alter federal drug policy in positive ways (my emphasis):
The anticipated selection of Chief Kerlikowske has given hope to those who want national drug policy to shift from an emphasis on arrest and prosecution to methods more like those employed in Seattle: intervention, treatment and a reduction of problems drug use can cause, a tactic known as harm reduction. Chief Kerlikowske is not necessarily regarded as having forcefully led those efforts, but he has not gotten in the way of them.
Under John P. Walters, the drug czar during most of the administration of President George W. Bush, the drug office focused on tough enforcement of drug laws, including emphases on marijuana and drug use among youths. The agency pointed to reductions in the use of certain kinds of drugs, but it was criticized by some local law enforcement officials who said its priorities did not reflect local concerns, from the rise of methamphetamine to the fight against drug smuggling at the Mexican border.